AbPlus™ Anti-AKR1B1 Magnetic Beads (VS-0724-YC598)

CAT#: VS-0724-YC598

The AbPlus Anti-AKR1B1 Magnetic Beads (VS-0724-YC598) is an innovative affinity resin which is bound with anti-AKR1B1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of AKR1B1 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line A-431 Figure 2 High expression in adrenal gland Figure 3 Low expression in cerebral cortex Figure 4 Kidney Figure 5 Testis Figure 6 RNA cell line category: Cell line enhanced (A549, BJ hTERT+, RPTEC TERT1, U-87 MG)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-AKR1B1 specific antibody
  • Target
  • AKR1B1
  • Immunogen
  • Recombinant human AKR1B1 fragment derived from E. coli.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
  • Alternative Names
  • Aldo-Keto Reductase Family 1 Member B; Aldo-Keto Reductase Family 1 Member B1; Aldose Reductase; EC 1.1.1.21; ALDR1; AR; Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase); Lii5-2 CTCL Tumor Antigen;
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