AbPlus™ Anti-AKR1B1 Magnetic Beads (VS-0724-YC598) (CAT#: VS-0724-YC598)
The AbPlus Anti-AKR1B1 Magnetic Beads (VS-0724-YC598) is an innovative affinity resin which is bound with anti-AKR1B1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of AKR1B1 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/231_D4_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/231_D4_2_selected.jpg

Figure 2 High expression in adrenal gland
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_5_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_5_5_val_selected.jpg

Figure 3 Low expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_9_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_9_5_val_selected.jpg

Figure 4 Kidney
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_9_5.jpg
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_9_5.jpg

Figure 5 Testis
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_5_6.jpg
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_5_6.jpg

Figure 6 RNA cell line category: Cell line enhanced (A549, BJ hTERT+, RPTEC TERT1, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000085662-AKR1B1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000085662-AKR1B1
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-AKR1B1 specific antibody
- Target
- AKR1B1
- Immunogen
- Recombinant human AKR1B1 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
- Alternative Names
- Aldo-Keto Reductase Family 1 Member B; Aldo-Keto Reductase Family 1 Member B1; Aldose Reductase; EC 1.1.1.21; ALDR1; AR; Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase); Lii5-2 CTCL Tumor Antigen;
- Gene ID
- 231
- UniProt ID
- P15121
Downloads
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MOB-3905z | Mouse Anti-AKR1B1 Recombinant Antibody (clone 18A5) | ELISA, IHC, WB | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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