Mouse Anti-AKR1B1 Recombinant Antibody (clone CBL022HM)
CAT#: VS7-HM61
Mouse Anti-AKR1B1 Recombinant Antibody (clone CBL022HM) is an mouse IgG antibody that recognizes the Human, Mouse, Dog, Rabbit AKR1B1 by WB.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/231_D4_2_selected.jpg
Normal Tissue
Figure 2 High expression in adrenal gland
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_5_5_val_selected.jpg
Normal Tissue
Figure 3 Low expression in cerebral cortex
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_9_5_val_selected.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_5_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (A549, BJ hTERT+, RPTEC TERT1, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000085662-AKR1B1
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Specifications
- Immunogen
- Antiserum was raised against a synthetic peptide derived from human AMPKα, encompassing the Thr172 phosphorylation site (amino acids 140-189).
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Mouse, Dog, Rabbit AKR1B1
- Species Reactivity
- Human, Mouse, Dog, Rabbit
- Clone
- CBL022HM
- Applications
- WB
- Conjugate
- None
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity-chromatography
- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- PBS
- Preservative
- 50% glycerol, 0.5% BSA, and 0.02% sodium azide.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice pack
Target
- Alternative Names
- AKR1B1; Low Km Aldose Reductase; Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase); Aldehyde Reductase 1; AR; Aldehyde Reductase; EC 1.1.1; ALDR1; Aldose Reductase; ALR2; EC 1.1.1.21; Aldo-Keto Reductase Family 1 Member B1
- UniProt ID
- P15121
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Cellular Localization
- Nucleoplasm, Plasma membrane, Microtubules, Mitotic spindle
- Function
- Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "AKR1B1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3905z | Mouse Anti-AKR1B1 Recombinant Antibody (clone 18A5) | ELISA, IHC, WB | Mouse IgG1, κ |
| MOB-0559MZ | Mouse Anti-AKR1B1 Recombinant Antibody (clone 2) | ELISA, WB | Mouse IgG2b |
| ZG-0268F | Mouse Anti-AKR1B1 Recombinant Antibody (ZG-0268F) | WB | Mouse IgG |
| ZG-0282F | Mouse Anti-AKR1B1 Recombinant Antibody (ZG-0282F) | WB | Mouse IgG |
| VS3-QX27 | Mouse Anti-AKR1B1 Recombinant Antibody (clone 4G9-B6-F6) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3952 | Hi-Affi™ Rabbit Anti-AKR1B1 Recombinant Antibody (clone SI12DS) | WB, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC598 | AbPlus™ Anti-AKR1B1 Magnetic Beads (VS-0724-YC598) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY83 | Anti-AKR1B1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY272 | Anti-Human AKR1B1 Immunohistochemistry Kit | IHC |
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