Mouse Anti-AKR1B1 Recombinant Antibody (clone CBL022HM) (CAT#: VS7-HM61)
Mouse Anti-AKR1B1 Recombinant Antibody (clone CBL022HM) is an mouse IgG antibody that recognizes the Human, Mouse, Dog, Rabbit AKR1B1 by WB.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/231_D4_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/231_D4_2_selected.jpg
Figure 2 High expression in adrenal gland
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_5_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_5_5_val_selected.jpg
Figure 3 Low expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_9_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26425/162056_B_9_5_val_selected.jpg
Figure 4 Kidney
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_9_5.jpg
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_9_5.jpg
Figure 5 Testis
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_5_6.jpg
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27391/162065_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (A549, BJ hTERT+, RPTEC TERT1, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000085662-AKR1B1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000085662-AKR1B1
Specifications
- Immunogen
- Antiserum was raised against a synthetic peptide derived from human AMPKα, encompassing the Thr172 phosphorylation site (amino acids 140-189).
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Mouse, Dog, Rabbit AKR1B1
- Species Reactivity
- Human, Mouse, Dog, Rabbit
- Clone
- CBL022HM
- Applications
- WB
- Conjugate
- None
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity-chromatography
- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- PBS
- Preservative
- 50% glycerol, 0.5% BSA, and 0.02% sodium azide.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice pack
Target
- Alternative Names
- AKR1B1; Low Km Aldose Reductase; Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase); Aldehyde Reductase 1; AR; Aldehyde Reductase; EC 1.1.1; ALDR1; Aldose Reductase; ALR2; EC 1.1.1.21; Aldo-Keto Reductase Family 1 Member B1
- UniProt ID
- P15121
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Cellular Localization
- Nucleoplasm, Plasma membrane, Microtubules, Mitotic spindle
- Function
- Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Recommended Products
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "AKR1B1"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
Antibody Magnetic Beads
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3905z | Mouse Anti-AKR1B1 Recombinant Antibody (clone 18A5) | ELISA, IHC, WB | Mouse IgG1, κ |
| MOB-0559MZ | Mouse Anti-AKR1B1 Recombinant Antibody (clone 2) | ELISA, WB | Mouse IgG2b |
| ZG-0268F | Mouse Anti-AKR1B1 Recombinant Antibody (ZG-0268F) | WB | Mouse IgG |
| ZG-0282F | Mouse Anti-AKR1B1 Recombinant Antibody (ZG-0282F) | WB | Mouse IgG |
| VS3-QX27 | Mouse Anti-AKR1B1 Recombinant Antibody (clone 4G9-B6-F6) | WB | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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