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DUSP1
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- APC-A*02:01/Human CL100 (QQFPGTAPKL) MHC Tetramer (MHC-CN0219)
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- Class: Class I
- Antigen: CL100
- Antigen Species: Human
- Peptide: QQFPGTAPKL
- Conjugate: APC
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- PE-A*02:01/Human CL100 (QQFPGTAPKL) MHC Tetramer (MHC-CN0220)
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- Class: Class I
- Antigen: CL100
- Antigen Species: Human
- Peptide: QQFPGTAPKL
- Conjugate: PE
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Langerhans cells)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enhanced (HHSteC, hTCEpi, REH)
Molecular function
Hydrolase, Protein phosphatase
More Types Infomation