EpCAM & Ad fiber knob
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Loading...- APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer (MHC-CN0031)
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- Class: Class I
- Antigen: Ep-CAM
- Antigen Species: Human
- Peptide: CLVMKAEM
- Conjugate: APC
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- PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer (MHC-CN0032)
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- Class: Class I
- Antigen: Ep-CAM
- Antigen Species: Human
- Peptide: CLVMKAEM
- Conjugate: PE
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For Research Use Only. Not For Clinical Use.
Background
Ad fiber knob is expressed in adenovirus.
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.