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KCNC1

KCNC1 (Potassium Voltage-Gated Channel Subfamily C Member 1) is a Protein Coding gene. This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Diseases associated with KCNC1 include Epilepsy, Progressive Myoclonic 7 and Spinocerebellar Ataxia 13.
Protein class

Disease related genes, FDA approved drug targets, Human disease related genes, Transporters, Voltage-gated ion channels

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Inhibitory neurons, Bipolar cells, Excitatory neurons)

Immune cell specificity

Group enriched (basophil, neutrophil)

Cell line specificity

Cell line enhanced (HeLa, RH-30, SCLC-21H, SH-SY5Y)

Interaction

Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity). Heteromultimer with KCNC2 (By similarity). Heterotetramer with KCNC3 (PubMed:23734863). Interacts with the ancillary subunits KCNE1 and KCNE2; the interaction modulates channel activity (By similarity).

Molecular function

Ion channel, Potassium channel, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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