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PAPOLA
Anti-PAPOLA Recombinant Antibody Products
- PE-A*02:01/Human PAP (ALDVYNGLL) MHC Tetramer (MHC-LC171)
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- Class: Class I
- Antigen: PAP
- Antigen Species: Human
- Peptide: ALDVYNGLL
- Conjugate: PE
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- APC-A*02:01/Human PAP (ALDVYNGLL) MHC Tetramer (MHC-LC172)
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- Class: Class I
- Antigen: PAP
- Antigen Species: Human
- Peptide: ALDVYNGLL
- Conjugate: APC
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- A*0201/Human PAP (ALDVYNGLL) MHC Tetramer (MHC-LC786)
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- Class: Class I
- Antigen: PAP
- Antigen Species: Human
- Peptide: ALDVYNGLL
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- A*02:01/Human PAP (ALDVYNGLL) MHC Monomer (MHC-YF166)
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- Class: Class I
- Antigen: PAP
- Antigen Species: Human
- Peptide: ALDVYNGLL
- Conjugate: Biotin
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3'-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Monomer. Found in a complex with CPSF1, FIP1L1 and PAPOLA. Interacts with AHCYL1 and FIP1L1; the interaction with AHCYL1 seems to increase interaction with FIP1L1 (PubMed:19224921). Interacts with NUDT21; the interaction is diminished by acetylation. Interacts with KPNB1; the interaction promotes PAP nuclear import and is inhibited by acetylation of PAP (By similarity).
Molecular function
RNA-binding, Transferase
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