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PTGR1

This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants.
Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Hepatocytes, Proximal tubular cells)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Cell line enhanced (OE19)

Interaction

Monomer or homodimer.

Molecular function

Oxidoreductase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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