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SERPINB6
SerpinB6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Inhibitor of cathepsin G, kallikrein-8 and thrombin may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Protein class
Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Forms a complex with the monomeric form of beta-tryptase.
Molecular function
Protease inhibitor, Serine protease inhibitor
More Types Infomation
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- Species Reactivity: Mouse
- Type: IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: IgG
- Application: ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.