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SOX21
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Squamous epithelial cells, Gastric mucus-secreting cells, Astrocytes, Oligodendrocyte precursor cells, Basal squamous epithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, NTERA-2)
Molecular function
Activator, DNA-binding
More Types Infomation
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, ICC, IF
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.