Enzymes
Intracellular, Membrane (different isoforms)
Group enriched (Early spermatids, Spermatocytes)
Low immune cell specificity
Low cell line specificity
Interacts (via C-terminal domain) with VCP. Interacts with AKT1; the interaction ubiquitinates AKT1 and leads to its proteasomal degradation. Interacts with MDM2; the interaction ubiquitinates AKT1 and leads to its proteasomal degradation. Interacts with p62/SQSTM1. Interacts with TRAF6 (PubMed:28087809). Interacts with IKBKG/NEMO (PubMed:25152375).
Transferase
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For Research Use Only. Not For Clinical Use.