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TTC4

This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90. Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs from upstream gene MROH (maestro heat-like repeat family member 7) to this gene.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts (via TPR repeats) with HSP90AB1 (PubMed:18320024). Interacts with HSPA8 and CDC6 (PubMed:18320024). Interacts with TBK1 (PubMed:29251827). Interacts with MSL1 (By similarity).

More Types Infomation

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