A*0201/CMV IE1 (VLAELVKQ) MHC Tetramer
CAT#: MHC-LC712
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HCMV-derived peptide of VLAELVKQ sequence covering 81-89 and A*0201 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- A*0201
- Class
- Class I
- MHC Species
- Human
- Antigen
- CMV IE1
- Antigen Species
- CMV
- Peptide
- VLAELVKQ
- Range
- 81-89
- Application
- FCM
Target
- Antigen Introduction
- Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). The major immediate-early (IE) gene of human cytomegalovirus (CMV) is believed to have a decisive role in acute infection and its activity is an important indicator of viral reactivation from latency. Although a variety of gene products are expressed from this region, the 72-kDa IE1 and the 86-kDa IE2 nuclear phosphoproteins are the most abundant and important. Both proteins have long been recognized as promiscuous transcriptional regulators.
- Alternative Names
- CMV IE1; Human cytomegalovirus IE1 protein; UL122
- Gene ID
- 3077563
- UniProt ID
- Q6SW29
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