A*0201/Human Leukocyte Proteinase-3 (VLQELNVTV) MHC Tetramer (CAT#: MHC-LC704)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Leukocyte Proteinase-3-derived peptide of VLQELNVTV sequence covering 169-177 and A*0201 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5938/1926_E2_5_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5938/1926_E2_5_selected.jpg
Figure 2 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17558/41299_B_6_4_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17558/41299_B_6_4_selected.jpg
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5938/80_C6_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5938/80_C6_1_blue_red_green.jpg
Figure 4 Bone marrow
(Hematopoietic cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5938/20979_B_4_4.jpg
(Hematopoietic cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5938/20979_B_4_4.jpg
Figure 5 RNA cell line category: Cell line enriched (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196415-PRTN3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196415-PRTN3
Figure 5 RNA cell line category: Cell line enriched (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196415-PRTN3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196415-PRTN3
Specifications
- Allele
- A*0201
- Class
- Class I
- MHC Species
- Human
- Antigen
- Leukocyte Proteinase-3
- Antigen Species
- Human
- Peptide
- VLQELNVTV
- Range
- 169-177
- Application
- FCM
Target
- Antigen Introduction
- Myeloblastin (EC 3.4.21.76, leukocyte proteinase 3, leukocyte proteinase 4, Wegener's granulomatosis autoantigen, proteinase PR-3, proteinase-3, PMNL proteinase) is an enzyme. This enzyme catalyses the following chemical reaction hydrolysis of proteins, including elastin. This enzyme is present in polymorphonuclear leukocyte granules.
- Alternative Names
- Prtn3; Proteinase 3; PR3; mPR3
- Gene ID
- 19152
- UniProt ID
- Q61096
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1082z | Mouse Anti-PRTN3 Recombinant Antibody (clone 41D8) | WB, ICC, IF, IHC, FuncS | Mouse IgG1 |
| MOB-0042MZ | Recombinant Mouse Anti-Human proteinase 3 Antibody (clone C429M) | ELISA | Mouse antibody |
| MRO-2139-CN | Rabbit Anti-PRTN3 Polyclonal Antibody (MRO-2139-CN) | WB, IF, IHC | Rabbit IgG |
| ZG-0397C | Mouse Anti-PRTN3 Recombinant Antibody (ZG-0397C) | WB, ELISA | Mouse IgG |
| VS3-QX923 | Mouse Anti-PRTN3 Recombinant Antibody (clone 3B4) | WB, IHC, ICC, FC, ELISA | Mouse IgG2b |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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