APC-A*24:02/HIV-1 Nef (RYPLTLGWCF) MHC Tetramer

CAT#: MHC-LC1800

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HIV-1 Nef-derived peptide of RYPLTLGWCF covering 143-152 and A*24:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • A*24:02
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • HIV-1 Nef
  • Antigen Species
  • HIV-1
  • Peptide
  • RYPLTLGWCF
  • Range
  • 143-152
  • Conjugate
  • APC

Target

  • Antigen Introduction
  • HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a major group (Group M) and two or more minor groups, namely Group N, O and possibly a group P. Each group is believed to represent an independent transmission of SIV into humans (but subtypes within a group are not). A total of 39 ORFs are found in all six possible reading frames (RFs) of HIV-1 complete genome sequence, but only a few of them are functional.
  • Alternative Names
  • HIV-1 Nef; Human immunodeficiency virus type-1 nef
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