APC-A2/Human DUSP5 (SLIGHLQTL) MHC Tetramer (CAT#: MHC-LC1952)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human DUSP5 of peptide SLIGHLQTL covering 337-345 and A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (hTERT-HME1, Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138166-DUSP5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138166-DUSP5
Specifications
- Allele
- A2
- Class
- Class I
- MHC Species
- Human
- Antigen
- DUSP5
- Antigen Species
- Human
- Peptide
- SLIGHLQTL
- Range
- 337-345
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008]
- Alternative Names
- DUSP5; Dual specificity protein phosphatase 5; DUSP; HVH3
- Gene ID
- 1847
- UniProt ID
- Q16690
Downloads
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|---|---|---|---|
| MOB-2358z | Mouse Anti-DUSP5 Recombinant Antibody (clone 44G5) | WB, ELISA, IF, IP | Mouse IgG3, κ |
| MOB-2095MZ | Recombinant Mouse Anti-Human DUSP5 Antibody (clone 3D8) | FC, ICC/IF, WB | Mouse antibody |
| MRO-1824-CN | Rabbit Anti-DUSP5 Polyclonal Antibody (MRO-1824-CN) | WB, IF | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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