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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    APC-B*14:02/Human CTSA (IRAAPPPLF) MHC Tetramer (CAT#: MHC-LC1437)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CTSA-derived peptide of IRAAPPPLF covering 2-10 and B*14:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31068/if_selected.jpg
    Figure 2 IF staining of human cell line SiHa
    Figure 2 IF staining of human cell line SiHa
    (Immunofluorescent staining of human cell line SiHa shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/72487/1891_I18_11_cr5bbd9e5de2447_selected.jpg
    Figure 3 IF staining of human cell line A-431
    Figure 3 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/24930/672_D5_6_selected.jpg
    Normal Tissue
    Figure 4 Adrenal gland
    Figure 4 Adrenal gland
    (High expression in adrenal gland)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31068/63425_B_4_5_val_selected.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/24930/55731_A_9_4.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/24930/55731_A_4_6.jpg
    Figure 7 Colon
    Figure 7 Colon
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/24930/55731_A_9_3.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (ASC diff)
    Figure 8 RNA cell line category: Cell line enhanced (ASC diff)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000064601-CTSA

    Specifications

    • Allele
    • B*14:02
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • CTSA
    • Antigen Species
    • Human
    • Peptide
    • IRAAPPPLF
    • Range
    • 2-10
    • Conjugate
    • APC
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis.
    • Alternative Names
    • CTSA; cathepsin A; GSL; GLB2; NGBE; PPCA; PPGB

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