APC-H-2Db/mimotope for DMK138-146 (MimA2) (YAIENYLEL) MHC Tetramer
CAT#: MHC-LC701
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of mimotope for MimA2-derived peptide of YAIENYLEL sequence and H-2Db molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Db
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- mimotope for DMK138-146 (MimA2)
- Antigen Species
- Zaire ebolavirus
- Peptide
- YAIENYLEL
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
- Alternative Names
- MimA2; mimotope for DMK138-146; Dystrophia myotonica protein kinase; DMPK
- Gene ID
- 911829
- UniProt ID
- Q05320
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC700 | PE-H-2Db/mimotope for DMK138-146 (MimA2) (YAIENYLEL) MHC Tetramer | FCM |
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