APC-H-2Kd/Plasmodium circumsporozoite protein (SYVPSAEQI) MHC Tetramer (CAT#: MHC-LC691)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Plasmodium circumsporozoite protein-derived peptide of SYVPSAEQI sequence covering 280-288 and H-2Kd molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
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  • Datasheet
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  • COA

Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • Antigen
  • Plasmodium circumsporozoite protein
  • Antigen Species
  • Plasmodium
  • Peptide
  • SYVPSAEQI
  • Range
  • 280-288
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Circumsporozoite protein (CSP) is a secreted protein of the sporozoite stage of the malaria parasite (Plasmodium sp.) and is the antigenic target of RTS,S, a pre-erythrocytic malaria vaccine currently undergoing clinical trials. The amino-acid sequence of CSP consists of an immunodominant central repeat region flanked by conserved motifs at the N- and C- termini that are implicated in protein processing as the parasite travels from the mosquito to the mammalian vector.
  • Alternative Names
  • PVX_091700; Plasmodium circumsporozoite protein; CSP

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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