APC-H-2Ld/Mycobacterium tuberculosis Ag85A (MPVGGQSSF) MHC Tetramer
CAT#: MHC-LC597
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MTB-derived peptide of MPVGGQSSF sequence covering 70-78 and H-2Ld molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Ld
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Mycobacterium tuberculosis Ag85A
- Antigen Species
- Mycobacterium tuberculosis
- Peptide
- MPVGGQSSF
- Range
- 70-78
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Mycobacterium tuberculosis is an obligate pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, M. tuberculosis can appear either Gram-negative or Gram-positive. Acid-fast stains such as Ziehl-Neelsen, or fluorescent stains such as auramine are used instead to identify M. tuberculosis with a microscope. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the tuberculin skin test, acid-fast stain, culture, and polymerase chain reaction.
- Alternative Names
- MTB Ag85A; Mycobacterium tuberculosis Ag85A
- Gene ID
- 886132
- UniProt ID
- P9WQP3
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC596 | PE-H-2Ld/Mycobacterium tuberculosis Ag85A (MPVGGQSSF) MHC Tetramer | FCM | |
| MHC-LC598 | BV421-H-2Ld/Mycobacterium tuberculosis Ag85A (MPVGGQSSF) MHC Tetramer | FCM |
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