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Recombinant Anti-BACE1 Single Domain Antibody (B9) (HPAB-0354-YC-VHH)

Described are single domain antibodies with a specificity for BACE1. More specifically, described are single variable-domain antibodies derived from camelids that bind to BACE1 and are capable of inhibiting the activity of BACE1. The antibodies can be used for research and medical applications. Specific applications include the use of BACE1-specific antibodies for the treatment of Alzheimer's disease.      

Specifications
Immunogen
Recombinant human BACE1
Host
Dromedary
Derivation
Phage display library
Type
Dromedary VHH
Specificity
Human BACE1
Species Reactivity
Human, Mouse
Clone
B9
Applications
ELISA, Functional Assay, Western Blotting
Related Disease
Alzheimer's disease
Target
Alternative Names
Beta-Site APP-Cleaving Enzyme 1; Membrane-Associated Aspartic Protease 2; Beta-Site APP Cleaving Enzyme 1; Aspartyl Protease 2; EC 3.4.23.46; Memapsin-2; Asp 2; BACE
Entrez Gene ID
23621
UniProt ID
P56817

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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