Mouse Anti-IGFLR1 Recombinant Antibody (clone CBL996)
CAT#: NEUT-1097CQ
This antibody is a mouse monoclonal antibody that binds specifically to IGFLR1, and it can neutralize the bioactivity of IGFLR1.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70778/1849_A10_11_cr5afc392c66691_selected.jpg
Normal Tissue
Figure 2 IHC staining of human hippocampus
Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12369/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12369/29065_B_7_5.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12369/29065_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12369/29065_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12369/29065_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12369/29065_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (HMC-1, Karpas-707, U-266/70)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126246-IGFLR1
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Specifications
- Immunogen
- Recombinant human IGFLR1
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human IGFLR1
- Species Reactivity
- Human
- Clone
- CBL996
- Applications
- Block, FC, CyTOF
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A or G purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Neutralizes IGFLR1 Activity
We used this mouse monoclonal antibody for blocking experiments. It effectively neutralized the bioactivity of IGFLR1 in our cell-based assays. It binds specifically and with high affinity.
Q&As
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Does this antibody block receptor function?
A: Yes, this mouse monoclonal antibody (clone CBL996) is capable of neutralizing the bioactivity of IGFLR1. It is validated for use in blocking assays.
-
What is the target specificity?
A: This antibody binds specifically to Human IGFLR1, which is a probable cell membrane receptor for the IGF-like family proteins. It binds IGFL1 and IGFL3 with higher affinity.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# NEUT-1097CQ, RRID: AB_3714107)
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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