BV421-BF2*04:01/Gallus gallus FUS (IDWFDGKE) MHC Tetramer
CAT#: MHC-LC1741
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of FUS-derived peptide of IDWFDGKE covering 319-326 and BF2*04:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8784/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33036/1894_G5_1_selected.jpg
Normal Tissue
Figure 3 IHC staining of human fallopian tube
Immunohistochemical staining of human fallopian tube shows strong nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8784/22362_A_9_7_selected.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33036/126298_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Peritubular cells Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33036/126298_A_6_6.jpg
Normal Tissue
Figure 6 Skin
Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75% Endothelial cells Staining: High Intensity: Strong Fibrohistiocytic cells Staining: High Intensity: Strong Hair follicles Staining: High Intensity: Strong Quantity:>75% Langerhans cells Staining: High Intensity: Strong Quantity:>75% Lymphocytes Staining: High Intensity: Strong Melanocytes Staining: High Intensity: Strong Quantity:>75% Vascular mural cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33036/126298_B_8_1.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33036/126298_A_9_8.jpg
Normal Tissue
Figure 8 Colon
Endocrine cells Staining: High Intensity: Strong Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Fibroblasts Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity:>75% Mucosal lymphoid cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33036/126298_A_9_3.jpg
Normal Tissue
Figure 9 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33036/126298_A_7_4.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089280-FUS
❮
❯
Specifications
- Allele
- BF2*04:01
- Class
- Class I
- MHC Species
- Chicken
- Antigen
- FUS/TLS
- Antigen Species
- Gallus gallus
- Peptide
- IDWFDGKE
- Range
- 319-326
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
- Alternative Names
- FUS; FUS RNA binding protein; FUS/TLS
- Gene ID
- 414144
- UniProt ID
- Q6J4Y8
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COA
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|---|---|---|---|
| MOB-4041z | Mouse Anti-FUS Recombinant Antibody (clone 44H2) | WB, ELISA, IF, IHC, IP | Mouse IgG1 |
| MRO-0614-CN | Rabbit Anti-FUS Recombinant Antibody (clone CBACN-233) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-CJ906 | Rabbit Anti-FUS Recombinant Antibody (VS3-CJ906) | WB, ICC, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1365 | Hi-Affi™ Rabbit Anti-FUS Recombinant Antibody (clone DS1365AB) | WB, IHC, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY875 | Anti-FUS Immunohistochemistry Kit | IHC | |
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