BV421-DRB1*01:01/MIG1 (AAYSDQATPLLLSPR) MHC Tetramer

CAT#: MHC-LC1240

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MIG1-derived peptide of AAYSDQATPLLLSPR covering 455-469 and DRB1*01:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • DRB1*01:01
  • Class
  • Class II
  • MHC Species
  • Human
  • Antigen
  • MIG1
  • Antigen Species
  • Saccharomyces cerevisiae
  • Peptide
  • AAYSDQATPLLLSPR
  • Range
  • 455-469
  • Conjugate
  • BV421
  • Application
  • FCM

Target

  • Antigen Introduction
  • Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state.
  • Alternative Names
  • MIG1; transcription factor MIG1; CAT4; SSN1; TDS22
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