BV421-DRB1*01:01/Human TPI1 (GELIGTLNAAKVPAD) MHC Tetramer (CAT#: MHC-LC1360)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of TPI1-derived peptide of GELIGTLNAAKVPAD covering 23-37 and DRB1*01:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/964_A10_1_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/964_A10_1_selected.jpg
Figure 2 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53568/if_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53568/if_selected.jpg
Figure 3 IHC staining of human parathyroid gland
(Immunohistochemical staining of human parathyroid gland shows moderate nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_3_8_selected.jpg
(Immunohistochemical staining of human parathyroid gland shows moderate nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_3_8_selected.jpg
Figure 4 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_9_4.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_5.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111669-TPI1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111669-TPI1
Specifications
- Allele
- DRB1*01:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- TPI1
- Antigen Species
- Human
- Peptide
- GELIGTLNAAKVPAD
- Range
- 23-37
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
- Alternative Names
- TPI1; triosephosphate isomerase 1; TIM; TPI; TPID; HEL-S-49
- Gene ID
- 7167
- UniProt ID
- P60174
Downloads
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| MOB-1644z | Mouse Anti-TPI1 Recombinant Antibody (clone 27C12) | ELISA, WB | Mouse IgG1 |
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| VS-0923-FY147 | Recombinant Mouse Anti-TPI1 Antibody (VS-0923-FY147) | ELISA, WB, IHC | Mouse IgG1 |
| VS-0923-FY148 | Recombinant Mouse Anti-TPI1 Antibody (VS-0923-FY148) | ELISA, WB, IHC | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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