BV421-DRB1*01:01/Human TPI1 (GELIGTLNAAKVPAD) MHC Tetramer (CAT#: MHC-LC1360)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of TPI1-derived peptide of GELIGTLNAAKVPAD covering 23-37 and DRB1*01:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/964_A10_1_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/964_A10_1_selected.jpg
Figure 2 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53568/if_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53568/if_selected.jpg
Figure 3 IHC staining of human parathyroid gland
(Immunohistochemical staining of human parathyroid gland shows moderate nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_3_8_selected.jpg
(Immunohistochemical staining of human parathyroid gland shows moderate nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_3_8_selected.jpg
Figure 4 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_9_4.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50924/148483_A_8_5.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111669-TPI1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111669-TPI1
Specifications
- Allele
- DRB1*01:01
- Class
- Class II
- Antigen
- TPI1
- Antigen Species
- Human
- Peptide
- GELIGTLNAAKVPAD
- Range
- 23-37
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
- Alternative Names
- TPI1; triosephosphate isomerase 1; TIM; TPI; TPID; HEL-S-49
- Gene ID
- 7167
- UniProt ID
- P60174
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1644z | Mouse Anti-TPI1 Recombinant Antibody (clone 27C12) | ELISA, WB | Mouse IgG1 |
| MOB-0840MZ | Recombinant Mouse Anti-Human TPI1 Antibody (clone P181) | ICC/IF | Mouse antibody |
| VS-0923-FY147 | Recombinant Mouse Anti-TPI1 Antibody (VS-0923-FY147) | ELISA, WB, IHC | Mouse IgG1 |
| VS-0923-FY148 | Recombinant Mouse Anti-TPI1 Antibody (VS-0923-FY148) | ELISA, WB, IHC | Mouse IgG2b |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3652 | Rabbit Anti-TPI1 Recombinant Antibody (clone DS3652AB) | WB, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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