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    Recombinant Anti-Ang2 × Anti-VEGFA Bispecific Antibody (Fab2)

    CAT#: FAB-L003

    Recombinant Anti-Ang2 & Anti-VEGFA Bispecific Antibody (Fab2) is composed of the Fab of the anti-Ang2 monoclonal antibody and Fab of an antibody specific for VEGFA. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG, and therefore it can be cleared from the blood naturally at a faster rate. This BsAb is capable of inhibiting signaling of their cognate proangiogenics and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone.It was designed for the treatment of renal cell carcinoma.

    Specifications

    • Target
    • Ang2 & VEGFA
    • Type
    • Fab2
    • Species Reactivity
    • Human
    • Target 1
    • Ang2
    • Host Species 1
    • Mouse
    • Target 2
    • VEGFA
    • Host Species 2
    • Mouse
    • Application
    • FuncS, Promising therapeutic agent
    • Related Disease
    • Age Related Macular Degeneration

    Target

    • Target 1
    • Ang2
    • Alternative Names
    • ANGPT2; angiopoietin 2; ANG2; AGPT2; angiopoietin-2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a
    • Target 2
    • VEGFA
    • Alternative Names
    • VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor
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    Datasheet

    Datasheet - FAB-L003.pdf

    MSDS

    MSDS - FAB-L003.pdf

    COA

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    CAT Product Name Application Type
    TAND-L042 Recombinant Anti-Ang2 × Anti-VEGFA Bispecific Antibody (Tandem Diabody) FuncS, Promising therapeutic agent Tandem Diabody
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