Recombinant Anti-BCMA × Anti-TACI Bispecific Antibody (CrossMab)
CAT#: CROSS-L016
Recombinant Anti-BCMA × Anti-TACI Bispecific Antibody (CrossMab) has been generated by applying the Crossmab format to generate an IgG shaped entity that binds each ligand with one arm. This BsAb is capable of inhibiting signaling of their cognate factors and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the treatment of BCMA-expressing multiple myeloma(MM).
Specifications
- Target
- BCMA & TACI
- Type
- CrossMab
- Species Reactivity
- Human
- Target 1
- BCMA
- Host Species 1
- Mouse
- Target 2
- TACI
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- BCMA-expressing multiple myeloma(MM)
Target
- Target 1
- BCMA
- Gene ID
- 608
- UniProt ID
- Q02223
- Alternative Names
- TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein
- Target 2
- TACI
- Gene ID
- 23495
- UniProt ID
- O14836
- Alternative Names
- TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAB-L008 | Recombinant Anti-BCMA × Anti-TACI Bispecific Antibody (Fab2) | FuncS, Promising therapeutic agent | Fab2 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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