Recombinant Anti-CD28 × Anti-MUC1 Bispecific Antibody (Fab2)

CAT#: FAB-L049

Recombinant Anti-CD28 × Anti-MUC1 Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD28 monoclonal antibody and Fab of an antibody specific for MUC1. A linker is added between the two Fab. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of Bile duct carcinoma (BDC).

Specifications

  • Target
  • CD28 & MUC1
  • Type
  • Fab2
  • Species Reactivity
  • Human
  • Target 1
  • CD28
  • Host Species 1
  • Mouse
  • Target 2
  • MUC1
  • Host Species 2
  • Mouse
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Bile duct carcinoma (BDC)

Target

  • Target 1
  • CD28
  • Alternative Names
  • CD28; CD28 molecule; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
  • Target 2
  • MUC1
  • Alternative Names
  • MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant
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