Recombinant Anti-CD3 × Anti-IL-2R Bispecific Antibody (Fab2) (CAT#: FAB-L015)
Recombinant Anti-CD3 × Anti-IL-2R Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD3 monoclonal antibody and Fab of an antibody specific for IL-2R. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG and therefore it clears from the blood naturally at a faster rate. This BsAb is capable of targeting the tumor, recruits T effector cells via binding to the CD3 subunit of the T cell receptor complex. It was designed for the treatment of T-cell lymphoma.
Specific Inquiry
Specifications
- Target
- CD3 & IL-2R
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- CD3
- Host Species 1
- Mouse
- Target 2
- IL-2R
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- HuT-102 cells
Target
- Target 1
- CD3
- Gene ID
- 916
- UniProt ID
- P01589
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex,
- Target 2
- IL-2R
- Gene ID
- 3559
- UniProt ID
- P07766
- Alternative Names
- IL2; interleukin 2; IL-2; TCGF; lymphokine; interleukin-2; T cell growth factor; involved in regulation of T-cell clonal expansion
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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