Recombinant Anti-CD4 × Anti-IL2 Bispecific Antibody (CrossMab)
CAT#: CROSS-L014
Recombinant Anti-CD4 × Anti-IL2 Bispecific Antibody (CrossMab) has been generated by applying the Crossmab format to generate an IgG shaped entity that binds each ligand with one arm. This BsAb is capable of inhibiting signaling of their cognate receptors and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the treatment of ADIS.
Specifications
- Target
- CD4 & IL2
- Type
- CrossMab
- Species Reactivity
- Human
- Target 1
- CD4
- Host Species 1
- Mouse
- Target 2
- IL2
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- ADIS
Target
- Target 1
- CD4
- Gene ID
- 920
- UniProt ID
- B4DT49
- Alternative Names
- CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3
- Target 2
- IL2
- Gene ID
- 3558
- UniProt ID
- P60568
- Alternative Names
- IL2; interleukin 2; IL-2; TCGF; lymphokine; interleukin-2; T cell growth factor; involved in regulation of T-cell clonal expansion
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