Recombinant Anti-CD8 × Anti-IL2 Bispecific Antibody (CrossMab)
CAT#: CROSS-L015
Recombinant Anti-CD8 × Anti-IL2 Bispecific Antibody (CrossMab) has been generated by applying the Crossmab format to generate an IgG shaped entity that binds each ligand with one arm. This BsAb is capable of inhibiting signaling of their cognate receptors and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the treatment of ADIS.
Specifications
- Target
- CD8 & IL2
- Type
- CrossMab
- Species Reactivity
- Human
- Target 1
- CD8
- Host Species 1
- Mouse
- Target 2
- IL2
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- ADIS
Target
- Target 1
- CD8
- Gene ID
- 925
- UniProt ID
- P01732
- Alternative Names
- CD8A; CD8a molecule; CD8; MAL; p32; Leu2; T-cell surface glycoprotein CD8 alpha chain; T8 T-cell antigen; T cell co-receptor; OKT8 T-cell antigen; T-cell antigen Leu2; Leu2 T-lymphocyte antigen; CD8 antigen, alpha polypeptide (p32); T-lymphocyte different
- Target 2
- IL2
- Gene ID
- 3558
- UniProt ID
- P60568
- Alternative Names
- IL2; interleukin 2; IL-2; TCGF; lymphokine; interleukin-2; T cell growth factor; involved in regulation of T-cell clonal expansion
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