Recombinant Anti-EGFR × Anti-CD2 Bispecific Antibody (Fab2)
CAT#: FAB-L057
Recombinant Anti-EGFR × Anti-CD2 Bispecific Antibody (Fab2) is composed of the Fab of the anti-EGFR monoclonal antibody and Fab of an antibody specific for CD2. A linker is added between the two Fab. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of Epithelial tumors.
Specifications
- Target
- EGFR & CD2
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- EGFR
- Host Species 1
- Human
- Target 2
- CD2
- Host Species 2
- Human
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Epithelial tumors
Target
- Target 1
- EGFR
- Gene ID
- 1956
- UniProt ID
- P00533
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;
- Target 2
- CD2
- Gene ID
- 914
- UniProt ID
- P06729
- Alternative Names
- CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor
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