Products

Anti-EGFR × Anti-Fcgr1 Bispecific Antibody (CrossMab, MDX447) (BSAB-L022)

Recombinant Anti-EGFR × Anti-Fcgr1 Bispecific Antibody (CrossMab). This bsAb has been generated by applying the Crossmab format to generate an IgGshaped entity that binds each ligand with one arm. It was designed for the treatment of Head and neck cancer, colorectal cancer.      

  • Datasheet

Specifications
Targets
EGFR & Fcgr1
Type
CrossMab
Expression Host
CHO
Species Reactivity
Human
Target 1
EGFR
Host
Humanized
Clone
H425
Target 2
Fcgr1
Host
Humanized
Clone
H22
Purity
>95% judged by SDS-PAGE under reducing condition
Related Disease
Head and neck cancer, colorectal cancer
Targets
Target 1
EGFR
Gene ID
1956
UniProt ID
P00533
Alternative Names
ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Target 2
Fcgr1
Gene ID
14129
UniProt ID
P26151
Alternative Names
CD64; IGGHAFC; AI323638; AV092959; FcgammaRI

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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