Recombinant Anti-FcαRI × Anti-EGFR Bispecific Antibody (Fab2) (CAT#: FAB-L027)
Recombinant Anti-FcαRI × Anti-EGFR Bispecific Antibody (Fab2) is composed of the Fab of the anti-FcαRI monoclonal antibody and Fab of an antibody specific for EGFR. A linker is added between the two Fab. This BsAb can retarget of immune cells to tumor cells. It was designed for the treatment of Epidermoid carcinoma.
Specific Inquiry
Specifications
- Target
- FcαRI & EGFR
- Type
- Fab2
- Target 1
- FcαRI
- Host Species 1
- Mouse
- Target 2
- EGFR
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Epidermoid carcinoma
Target
- Target 1
- FcαRI
- Gene ID
- 2204
- UniProt ID
- P24071
- Alternative Names
- FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
- Target 2
- EGFR
- Gene ID
- 1956
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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