Recombinant Anti-FcγRI × Anti-HLA class II Bispecific Antibody (Fab2)
CAT#: FAB-L042
Recombinant Anti-FcγRI × Anti-HLA class II Bispecific Antibody (Fab2) is composed of the Fab of the anti-FcγRI monoclonal antibody and Fab of an antibody specific for HLA class II. A linker is added between the two Fab. This BsAb can retarget of neutrophils to tumor cells. It was designed for the treatment of Lymphoma .
Specifications
- Target
- FcγRI & HLA class II
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- FcγRI
- Host Species 1
- Mouse
- Target 2
- HLA class II
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Lymphoma
Target
- Target 1
- FcγRI
- Gene ID
- 2209
- UniProt ID
- P12314
- Alternative Names
- CD64; FCRI; CD64A; IGFR1
- Target 2
- HLA class II
- Gene ID
- 3123
- UniProt ID
- P01912
- Alternative Names
- HLA-DRB1; major histocompatibility complex, class II, DR beta 1; SS1; DRB1; DRw10; HLA-DRB; HLA-DR1B; DW2.2/DR2.2; HLA class II histocompatibility antigen, DR-1 beta chain; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MHC class II antigen; human leucocyte antigen DRB1; lymphocyte antigen DRB1
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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