Recombinant Anti-FcγRI × Anti-HLA class II Bispecific Antibody (Fab2)

CAT#: FAB-L042

Recombinant Anti-FcγRI × Anti-HLA class II Bispecific Antibody (Fab2) is composed of the Fab of the anti-FcγRI monoclonal antibody and Fab of an antibody specific for HLA class II. A linker is added between the two Fab. This BsAb can retarget of neutrophils to tumor cells. It was designed for the treatment of Lymphoma .

Specifications

  • Target
  • FcγRI & HLA class II
  • Type
  • Fab2
  • Species Reactivity
  • Human
  • Target 1
  • FcγRI
  • Host Species 1
  • Mouse
  • Target 2
  • HLA class II
  • Host Species 2
  • Mouse
  • Related Disease
  • Lymphoma

Target

  • Target 1
  • FcγRI
  • Alternative Names
  • CD64; FCRI; CD64A; IGFR1
  • Target 2
  • HLA class II
  • Alternative Names
  • HLA-DRB1; major histocompatibility complex, class II, DR beta 1; SS1; DRB1; DRw10; HLA-DRB; HLA-DR1B; DW2.2/DR2.2; HLA class II histocompatibility antigen, DR-1 beta chain; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MHC class II antigen; human leucocyte antigen DRB1; lymphocyte antigen DRB1
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