Recombinant Anti-FcγRI × Anti-MHC class II Bispecific Antibody (Fab2) (CAT#: FAB-L047)
Recombinant Anti-FcγRI × Anti-MHC class II Bispecific Antibody (Fab2) is composed of the Fab of the anti-FcγRI monoclonal antibody and Fab of an antibody specific for MHC class II. A linker is added between the two Fab. This BsAb can retarget of immune cells to tumor cells. It was designed for the treatment of B cell lymphoma.
Specific Inquiry
Specifications
- Target
- FcγRI & MHC class II
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- FcγRI
- Host Species 1
- Mouse
- Target 2
- MHC class II
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- B cell lymphoma
Target
- Target 1
- FcγRI
- Gene ID
- 2209
- UniProt ID
- P12314
- Alternative Names
- FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1
- Target 2
- MHC class II
- Gene ID
- 972
- UniProt ID
- P04233
- Alternative Names
- Cd74; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); Ii; CLIP; DHLAG; HLADG; Ia-GAMMA
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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