D8-MMAE

CAT#: ADCsR-021CL

D8-MMAE(D8-Monomethyl auristatin E; D8-Vedotin) is a deuterated form of MMAE.

Specifications

  • Synonyms
  • D8-Monomethyl auristatin E; D8-Vedotin; D8 MMAE
  • Formula
  • C39H59D8N5O7
  • Molecular Weight
  • 726.03
  • Purity
  • >98%
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Breast cancer biomarkers at key points during disease progression
Useful Deuterated Standard
We acquired this deuterated MMAE for use as an internal standard in our mass spectrometry analysis of ADC metabolites. The high isotopic purity (>98%) provided clean signals and allowed for accurate quantification of the drug in our samples.
Breast cancer biomarkers at key points during disease progression
Convenient DMSO Solution
Providing this toxin dissolved in DMSO was very convenient for our workflows. It saved us preparation time and ensured the concentration was accurate. It functioned perfectly as a control for identifying the specific pathways of cell cycle damage.

Q&As

  1. What is D8-MMAE and how is it used?

    A: D8-MMAE, also known as D8-Vedotin, is a deuterated form of Monomethyl auristatin E. It is primarily used as an analytical standard or reagent in ADC research, for example in mass spectrometry to track metabolites or drug release.

  2. What solvent is this product supplied in?

    A: This D8-MMAE product is supplied at a concentration of 10 mM in DMSO (Dimethyl sulfoxide). This solvent is chosen to ensure the solubility and stability of the hydrophobic auristatin payload for research applications.

View the frequently asked questions answered by Creative Biolabs Support.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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