PE-A*02:01/Human RPLP2 (ILDSVGIEA) MHC Tetramer
CAT#: MHC-LC4313
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human RPLP2 of peptide ILDSVGIEA covering 26-34 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nuclear speckles & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75365/2031_F2_1_selected.jpg
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- RPLP2
- Antigen Species
- Human
- Peptide
- ILDSVGIEA
- Range
- 26-34
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
- Alternative Names
- RPLP2; 60S acidic ribosomal protein P2; P2; LP2; RPP2; D11S2243E
- Gene ID
- 6181
- UniProt ID
- P05387
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