PE-A*02:01/Human TSC22D3 (SLLGGDVVSV) MHC Tetramer
CAT#: MHC-LC1928
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TSC22D3 of peptide SLLGGDVVSV covering 27-36 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1916/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human spleen
Immunohistochemical staining of human spleen shows moderate cytoplasmic positivity in cells in white pulp.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34364/ihc_selected.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34364/131693_A_7_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34364/131693_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34364/131693_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34364/131693_A_8_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HHSteC, hTCEpi, Karpas-707)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157514-TSC22D3
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- TSC22D3
- Antigen Species
- Human
- Peptide
- SLLGGDVVSV
- Range
- 27-36
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
- Alternative Names
- TSC22D3; TSC22 domain family protein 3; DIP; GILZ; DSIPI; TSC-22R
- Gene ID
- 1831
- UniProt ID
- Q99576
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| MOB-3096z | Mouse Anti-TSC22D3 Recombinant Antibody (clone 30A7) | ELISA, IF, IHC, WB | Mouse IgG1, κ |
| MOB-0768CT | Recombinant Mouse anti-Human TSC22D3 Monoclonal antibody (EML327) | ICC, IF, IHC-P, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1948 | PE-A2/Human TSC22D3 (SLLGGDVVSV) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2379 | Anti-TSC22D3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7568 | Anti-Human TSC22D3 Immunohistochemistry Kit | IHC |
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