PE-A*08:01/CMV MLE (ELKRKMIYM) MHC Tetramer (CAT#: MHC-LC1034)

• Allele
• A*08:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• CMV MIE

• Antigen Species
• CMV

• Peptide
• ELKRKMIYM

• Range
• 51-59

• Conjugate
• PE

• Application
• FCM

• Antigen Introduction
• Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). The major immediate-early (IE) gene of human cytomegalovirus (CMV) is believed to have a decisive role in acute infection and its activity is an important indicator of viral reactivation from latency. Although a variety of gene products are expressed from this region, the 72-kDa IE1 and the 86-kDa IE2 nuclear phosphoproteins are the most abundant and important. Both proteins have long been recognized as promiscuous transcriptional regulators.

• Alternative Names
• MLE; Major immediate-early protein

• Gene ID
• 3077445

• UniProt ID
• Q9YRL3

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