PE-A*08:01/CMV MLE (ELKRKMIYM) MHC Tetramer

CAT#: MHC-LC1034

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CMV MLE-derived peptide of ELKRKMIYM covering 51-59 and A*08:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • A*08:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • CMV MIE
  • Antigen Species
  • CMV
  • Peptide
  • ELKRKMIYM
  • Range
  • 51-59
  • Conjugate
  • PE

Target

  • Antigen Introduction
  • Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). The major immediate-early (IE) gene of human cytomegalovirus (CMV) is believed to have a decisive role in acute infection and its activity is an important indicator of viral reactivation from latency. Although a variety of gene products are expressed from this region, the 72-kDa IE1 and the 86-kDa IE2 nuclear phosphoproteins are the most abundant and important. Both proteins have long been recognized as promiscuous transcriptional regulators.
  • Alternative Names
  • MLE; Major immediate-early protein
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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