PE-A*68:01/Human hP (MSLQRQFLR) MHC Tetramer (CAT#: MHC-LC2819)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human hP of peptide MSLQRQFLR and A*68:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/1309_F11_1_selected.jpg

(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/ihc_selected.jpg

(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66795/170921_A_6_6_selected.jpg

(Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/788_B12_1_red_green.jpg

(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/118508_A_9_4.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000257017-HP

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000257017-HP
Specifications
- Allele
- A*68:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- hP
- Antigen Species
- Human
- Peptide
- MSLQRQFLR
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- In biochemistry, a hypothetical protein is a protein whose existence has been predicted, but for which there is a lack of experimental evidence that it is expressed in vivo. Sequencing of several genomes has resulted in numerous predicted open reading frames to which functions cannot be readily assigned. These proteins, either orphan or conserved hypothetical proteins, make up ~ 20% to 40% of proteins encoded in each newly sequenced genome. Even when there is enough evidence that the product of the gene is expressed, by techniques such as microarray and mass-spectrometry, it is difficult to assign a function to it given its lack of identity to protein sequences with annotated biochemical function. Nowadays, most protein sequences are inferred from computational analysis of genomic DNA sequence. Hypothetical proteins are created by gene prediction software during genome analysis. When the bioinformatic tool used for the gene identification finds a large open reading frame without a characterised homologue in the protein database, it returns "hypothetical protein" as an annotation remark.
- Alternative Names
- hP; hypothetical protein
Downloads
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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