PE-A*69:01/Human ETS1 (YTSDYFISY) MHC Tetramer (CAT#: MHC-LC4415)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human ETS1 of peptide YTSDYFISY covering 154-162 and A*69:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63230/1151_D9_1_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63230/1151_D9_1_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2575/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2575/if_selected.jpg
Figure 3 High expression in lymph node.
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2575/6349_A_8_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2575/6349_A_8_8.jpg
Figure 4 Tonsil
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2575/6349_A_5_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2575/6349_A_5_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HEL, JURKAT, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134954-ETS1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134954-ETS1
Specifications
- Allele
- A*69:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- ETS1
- Antigen Species
- Human
- Peptide
- YTSDYFISY
- Range
- 154-162
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
- Alternative Names
- ETS1; Protein C-ets-1; p54; ETS-1; EWSR2; c-ets-1
- Gene ID
- 2113
- UniProt ID
- P14921
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3991z | Mouse Anti-ETS1 Recombinant Antibody (clone 25F12) | ELISA, FC, IF, IHC, WB | Mouse IgG1 |
| MRO-0557-CN | Rabbit Anti-ETS1 Recombinant Antibody (clone JM92-32) | WB, IHC, FC | Rabbit IgG |
| VS3-QX392 | Mouse Anti-ETS1 Recombinant Antibody (clone 8A8) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-XY654 | Mouse Anti-ETS1 Recombinant Antibody (clone 10D2) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-FY524 | Recombinant Rabbit Anti-ETS1 Antibody (clone R04-8C7) | WB | Rabbit IgG |
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