PE-B*35:01/HIV pol (VPLDEDFRKY) MHC Tetramer (CAT#: MHC-LC278)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HIV-derived peptide of VPLDEDFRKY sequence covering 273-282 and B*35:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
Specifications
- Allele
- B*35:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- HIV pol
- Antigen Species
- HIV-1
- Peptide
- VPLDEDFRKY
- Range
- 273-282
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a major group (Group M) and two or more minor groups, namely Group N, O and possibly a group P. Each group is believed to represent an independent transmission of SIV into humans (but subtypes within a group are not). A total of 39 ORFs are found in all six possible reading frames (RFs) of HIV-1 complete genome sequence, but only a few of them are functional.
- Alternative Names
- HIV-1 pol; Human immunodeficiency virus type-1 pol
- Gene ID
- 155348
- UniProt ID
- P04585
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