PE-B*44:02/Human HLA-DPA1 (EEFGRAFSF) MHC Tetramer
CAT#: MHC-LC1202
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HLA-DPA1-derived peptide of EEFGRAFSF covering 77-85 and B*44:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17967/1639_G1_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17967/41094_B_7_5.jpg
Normal Tissue
Figure 3 Testis
Spermatogonia cells Staining: Low Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17967/41094_A_5_6.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17967/41094_A_8_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, REH, U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000231389-HLA-DPA1
❮
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Specifications
- Allele
- B*44:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- HLA-DPA*0201
- Antigen Species
- Human
- Peptide
- EEFGRAFSF
- Range
- 77-85
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
- Alternative Names
- HLA-DPA1; Major histocompatibility complex, class II, DP alpha 1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DP1A
- Gene ID
- 3113
- UniProt ID
- Q95HB9
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| MOB-1980z | Mouse Anti-HLA-DPA1 Recombinant Antibody (clone 3F10) | ELISA, WB | Mouse IgG2a, κ |
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| MOB-0049MZ | Recombinant Mouse Anti-Human HLA, Class II antigen-DR+DP Antibody (clone A237-14241) | FC, IP | Mouse antibody |
| CAT | Product Name | Application | Type |
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| MHC-LC1250 | PE-B*44:05/Human HLA-DPA1 (EEFGRAYGF) MHC Tetramer | FCM |
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| MHC-LC1514 | PE-B*44:02/Human HLA-DPA1 (EEAGRAFSF) MHC Tetramer | FCM |
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| MHC-LC1517 | PE-B*44:02/Human HLA-DPA1 (EEFGAAFSF) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
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| MHC-LC1520 | PE-B*44:02/Human HLA-DPA1 (EEFGRAASF) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
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| MHC-LC1523 | PE-B*44:02/Human HLA-DPA1 (EEAGAAFSF) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-CJ760 | Mouse Anti-HLA-DPA1 Recombinant Antibody (clone B7/21) | IF, FC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
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| VS3-FY678 | Recombinant Mouse Anti-HLA-DPA1 Antibody (clone 2B1A10) | ELISA, WB, IHC, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
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| VS3-FY679 | Recombinant Mouse Anti-HLA-DPA1 Antibody (clone 6C3D8) | ELISA, IHC, FC | Mouse IgG2b |
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