PE-B7/Human ARID3A (SPKLPVSSL) MHC Tetramer
CAT#: MHC-LC1970
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human ARID3A of peptide SPKLPVSSL covering 372-380 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76330/1832_F6_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line K-562
Immunofluorescent staining of human cell line K-562 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76330/1892_C8_1_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76330/1890_A10_1_cr5b9b86ed1d259_red_green.jpg
Normal Tissue
Figure 4 Placenta
Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76330/165564_A_1_7.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76330/165564_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (BEWO, CACO-2, Hep G2, K-562, THP-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000116017-ARID3A
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Specifications
- Allele
- B7
- Class
- Class I
- MHC Species
- Human
- Antigen
- ARID3A
- Antigen Species
- Human
- Peptide
- SPKLPVSSL
- Range
- 372-380
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
- Alternative Names
- ARID3A; AT-rich interactive domain-containing protein 3A; DRIL1; DRIL3; BRIGHT; E2FBP1
- Gene ID
- 1820
- UniProt ID
- Q99856
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COA
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