PE-B7/Human IL2RG (KPSLPFTSL) MHC Tetramer (CAT#: MHC-LC1971)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human IL2RG of peptide KPSLPFTSL covering 3-11 and B7 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49691/1577_G8_2_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49691/1577_G8_2_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147168-IL2RG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147168-IL2RG
Figure 2 RNA cell line category: Cell line enriched (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147168-IL2RG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147168-IL2RG
Specifications
- Allele
- B7
- Class
- Class I
- MHC Species
- Human
- Antigen
- IL2RG
- Antigen Species
- Human
- Peptide
- KPSLPFTSL
- Range
- 3-11
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]
- Alternative Names
- IL2RG; Cytokine receptor common gamma chain precursor; P64; CIDX; IMD4; CD132; SCIDX; IL-2RG; SCIDX1
- Gene ID
- 3561
- UniProt ID
- P31785
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For Research Use Only. Not For Clinical Use.
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