PE-DQB1*03:02/Human HLA-DQA1 (YLTFLPSADEIYDCKV) MHC Tetramer (CAT#: MHC-LC4541)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HLA-DQA1 of peptide YLTFLPSADEIYDCKV covering 175-190 and DQB1*03:02 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Allele
  • DQB1*03:02
  • Class
  • Class II
  • Antigen
  • HLA-DQA1
  • Antigen Species
  • Human
  • Peptide
  • YLTFLPSADEIYDCKV
  • Range
  • 175-190
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • HLA-DQA1; HLA class II histocompatibility antigen, DQ(2) alpha chain; DQ-A1; CELIAC1; HLA-DQA

Downloads

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Recombinant Antibody

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MOB-1318z Mouse Anti-HLA-DQA1 Recombinant Antibody (clone 39D5) FC, ICC, IF, IHC Mouse IgG2a, κ
MRO-0751-CN Rabbit Anti-HLA-DQA1 Recombinant Antibody (clone JU17-34) WB, IHC, IP Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1621 Rabbit Anti-HLA-DQA1 Recombinant Antibody (clone DS1621AB) WB, IHC, IP Rabbit IgG

MHC Tetramer for Cancer

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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