PE-Gogo-B*0101/Human ACTA1 (KRGILTLKY) MHC Tetramer
CAT#: MHC-LC3038
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human ACTA1 of peptide KRGILTLKY covering 63-71 and Gogo-B*0101 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 High expression in skeletal muscle.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45/300_B_2_6_val_selected.jpg
Normal Tissue
Figure 2 Low expression in skin 1.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45/300_B_9_1_val_selected.jpg
Normal Tissue
Figure 3 Heart muscle
Cardiomyocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45/300_B_5_6.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (BEWO)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143632-ACTA1
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Specifications
- Allele
- Gogo-B*0101
- Class
- Class I
- MHC Species
- Gorilla
- Antigen
- ACTA1
- Antigen Species
- Human
- Peptide
- KRGILTLKY
- Range
- 63-71
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
- Alternative Names
- ACTA1; Actin, alpha skeletal muscle; ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; SHPM; CFTD1; CFTDM
- Gene ID
- 58
- UniProt ID
- P68133
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Datasheet
MSDS
COA
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|---|---|---|---|
| MOB-1782MZ | Mouse Anti-ACTA1 Recombinant Antibody (clone 6D6.G9.D8) | IHC-P | Mouse IgM |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-006 | Recombinant Human Anti-ACTA1 Antibody (C2507) | WB, ELISA, IF, FuncS | IgG |
| PABX-006-F (E) | Recombinant Human Anti-ACTA1 Antibody Fab Fragment (C2507) | WB, ELISA, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-006-S (P) | Recombinant Human Anti-ACTA1 Antibody scFv Fragment (C2507) | WB, ELISA, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0047 | Hi-Affi™ Rabbit Anti-ACTA1 Recombinant Antibody (clone DS47AB) | WB, IHC-P, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY3 | AbPlus™ Anti-ACTA1 Magnetic Beads (JF47-01) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY105 | Anti-ACTA1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY106 | Anti-Rat ACTA1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY107 | Anti-Mouse ACTA1 Immunohistochemistry Kit | IHC | |
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