PE-Mamu-B*001:01/Human TJP2 (YDYHSSSEKL) MHC Tetramer (CAT#: MHC-LC4335)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TJP2 of peptide YDYHSSSEKL covering 426-435 and Mamu-B*001:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1813/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1813/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70714/1351_F6_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70714/1351_F6_2_selected.jpg
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/if_selected.jpg
Figure 4 Placenta
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/27363_A_2_7.jpg
(Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/27363_A_2_7.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/27363_A_9_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/27363_A_9_8.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/27363_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9228/27363_A_8_5.jpg
Figure 7 RNA cell line category: Cell line enhanced (A-431)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000119139-TJP2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000119139-TJP2
Specifications
- Allele
- Mamu-B*001:01
- Class
- Class I
- MHC Species
- Macaca
- Antigen
- TJP2
- Antigen Species
- Human
- Peptide
- YDYHSSSEKL
- Range
- 426-435
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
- Alternative Names
- TJP2; Tight junction protein 2 (zona occludens 2) isoform 1; ZO2; X104; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11
- Gene ID
- 9414
- UniProt ID
- Q9UDY2
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2291-CN | Rabbit Anti-TJP2 Polyclonal Antibody (MRO-2291-CN) | WB, IF | Rabbit IgG |
| MRO-0247YJ | Mouse Anti-TJP2 Recombinant Antibody (clone CBS190) | ELISA, ICC, IF, WB, IHC, IP, FC | Mouse IgG1, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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