Quinaldopeptin
CAT#: ADCsR-227CL
Quinaldopeptin is a quinomycin antibiotic isolated from an Amycolatopsis sp. with strong antimicrobial and cytotoxic activity. The symmetric peptide structure of Quinaldopeptin contains two intercalating naphtyl moieties which produce a bis-intercalation of DNA base pairs, creating DNA crosslinks and disturbing natural DNA processes. Quinaldopeptin is demonstrated to have high efficacy against gram-positive bacteria and cultured B16 melanoma cells. Quinaldopeptin is related to sandramycin and luzopeptins.
Specifications
- Synonyms
- Antibiotic BMY 28662; Antibiotic BU 3845T
- Formula
- C62H78N14O14
- CAS No.
- 130743-07-6
- Molecular Weight
- 1243,37 g/mol
- Purity
- 95%
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