Mouse Anti-BACE1 Recombinant Antibody (clone 18H11)

Name: Mouse Anti-BACE1 Recombinant Antibody (clone 18H11)
SKU: MOB-2939z
Rating: 5 (1 reviews)

CAT#: MOB-2939z

This product is a mouse antibody that recognizes human BACE1. It can be used in the following applications: WB, ELISA, FCM, ICC.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/952_G12_1_selected.jpg

Subcellular Location and Protein Expression Figure 2 IHC staining of human pancreas

Immunohistochemical staining of human pancreas shows cytoplasmic positivity.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_A_1_3_selected.jpg

Subcellular Location and Protein Expression Figure 3 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/947_G12_1_blue_red_green.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_B_7_5.jpg

Normal Tissue Figure 5 Hippocampus

Glial cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_B_8_6.jpg

Normal Tissue Figure 6 Colon

Glandular cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_A_7_3.jpg

Normal Tissue Figure 7 Liver

Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_A_9_4.jpg

Normal Tissue Figure 8 Kidney

Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_A_9_5.jpg

Normal Tissue Figure 9 Testis

Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining:Medium
Intensity: Moderate
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_A_5_6.jpg

Normal Tissue Figure 10 Lymph node

Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16358/35706_A_7_8.jpg

RNA Expression Figure 11 RNA cell line category: Cell line enhanced (fHDF/TERT166)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186318-BACE1

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Specifications

Immunogen
Human Beta-Site APP-Cleaving Enzyme 1

Host Species
Mouse

Derivation
Mouse

Type
Mouse IgG1

Specificity
Human BACE1

Species Reactivity
Human

Clone
18H11

Applications
WB, ELISA, FC, ICC

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
This antibody has been reported for use in Western blot, Enzyme-linked Immunosorbent Assay, Flow Cytometry, Immunocytochemistry.

Target

Alternative Names
BACE1; Memapsin 2); Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1; Memapsin-2; Membrane-Associated Aspartic Protease 2; Beta-Secretase 1; APP Beta-Secretase; ASP2; KIAA1149; Beta-Site APP-Cleaving Enzyme; Beta-Site APP Cleaving Enzyme 1; Beta-Site

UniProt ID
P56817

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-2939z.pdf

MSDS

MSDS - MOB-2939z.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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